Publications

Mesa-Diaz, N., & Du, L. (2021). Developing miR-506-3p Mimics with Enhanced Differentiation-Inducing Activity. FASEB Journal, 35(No.1 Suppl). Retrieved from https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supplement.634.5

Zhao, G., Du, L., Zhang, L., & Jia, Y. (2021). LIM domain only 1: an oncogenic transcription cofactor contributing to the tumorigenesis of multiple cancer types. Chinese Medicine Journal, 134(9), 1017–1030. https://doi.org/10.1097/CM9.0000000000001487

Aksenov, N. A., Aksenov, A. V., Kirilov, N. K., Arutiunov, N. A., Aksenov, D. A., Maslivetc, V., … Kornienko, A. V. (2020). Nitroalkanes as electrophiles: synthesis of triazole-fused heterocycles with neuroblastoma differentiation activity. Organic & Biomolecular Chemistry, 18(34), 6651–6664. https://doi.org/https://doi.org/10.1039/D0OB01007C

Eyong, K. O., Ketsemen, H. L., Zhao, Z., Du, L., Ingels, A., Mathieu, V., … Romo, D. (2020). Anti-proliferative activity of naphthoquinones and indane carboxylic acids from lapachol against a panel of human cancer cell lines. Medicinal Chemistry Research, 29, 1058–1066.

Baker, A. L., Zhao, Z., & Du, L. (2020). Investigation of the Oncogenic Role of the Cell Cycle Regulator SAPCD2 in Pediatric Neuroblastoma. FASEB Journal, 34(No.1 Suppl). Retrieved from https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supplement.634.5

Zhao, Z., Shelton, S. D., Oviedo, A., Baker, A. L., Bryant, C. P., Omidvarnia, S., & Du, L. (2020). The PLAGL2/MYCN/miR-506-3p interplay regulates neuroblastoma cell fate and associates with neuroblastoma progression. Journal of Experimental and Clinical Cancer Research, 39(1), 41. https://doi.org/10.1186/s13046-020-1531-2.

Kosti, A., Du, L., Shivram, H., Qiao, M., Burns, S., Garcia, J. G., … Penalva LOF. (2019). The ELF4 Is a Target of miR-124 and Promotes Neuroblastoma Proliferation and Undifferentiated State. Molecular Cancer Research : MCR, 18(1), 68–78. https://doi.org/10.1158/1541-7786.MCR-19-0187

Aksenov, A. V., Aksenov, D. A., Arutiunov, N. A., Aksenov, N. A., Aleksandrova, E. V., Zhao, Z., … Rubin, M. (2019). Synthesis of Spiro[indole-3,5’-isoxazoles] with Anticancer Activity via a Formal [4 + 1]-Spirocyclization of Nitroalkenes to Indoles. The Journal of Organic Chemistry, 84(11), 7123–7137. https://doi.org/10.1021/acs.joc.9b00808

Jemal, M. A., Schwartz, Z. T., Zhao, Z., Du, L., Du, L., Du, L. D., … Du, L. M. (2019). Overcoming the Rapid Metabolism of the Promising Anticancer Natural Product Rooperol. FASEB Journal, 33(No.1 Suppl). Retrieved from https://www.fasebj.org/doi/abs/10.1096/fasebj.2019.33.1_supplement.634.5

Rastogi, S. K., Zhao, Z., Barrett, S. L., Shelton, S. D., Zafferani, M., Anderson, H. E., … Brittain, W. J. (2018). Photoresponsive azo-combretastatin A-4 analogues. EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY, 143, 1–7. https://doi.org/10.1016/j.ejmech.2017.11.012

Zhao, Z., Partridge, V., Sousares, M., Shelton, S., Holland, C., Pertsemlidis, A., & Du, L. (2018). microRNA-2110 functions as a tumor suppressor in neuroblastoma by directly targeting Tsukushi. PLos One, 13(12), e0208777.

Du, L., Zhao, Z., Milind, S., Shelton, S. S., Tzu-Hung, H., Ma, X., … Pertsemlidis, A. (2018). LMO1 functions an oncogene through regulating TTK expression and correlates with neuroendocrine differentiation of lung cancer. Oncotarget, 9, 29601–29618.

Shelton, S. D., Zhao, Z., & Du, L. (2018). RXRA is a direct target gene of miR-506-3p that regulates oncogene MYCN expression and cell differentiation in neuroblastoma. FASEB Journal, 32(No.1 Suppl). Retrieved from www.fasebj.org/content/32/1_Supplement/804.16

Medrano, G., Zhao, Z., & Du, L. (2018). The Role of the Vacuolar (H+)-ATPase in Neuroblastoma Cell Differentiation induced by microRNA 506-3p. FASEB Journal, 32(No.1 Suppl). Retrieved from www.fasebj.org/content/32/1_Supplement/804.3

Yu, X., Zhang, Y., Cavazos, D., Ma, X., Zhao, Z., Du, L., & Pertsemlidis, A. (2018). miR-195 targets cyclin D3 and survivin to modulate the tumorigenesis of non-small cell lung cancer. Cell Death and Disease, 9(2), 193.

Sousares, M., Partridge, V., Weigum, S., & Du, L. (2017). MicroRNAs in neuroblastoma differentiation and differentiation therapy. Advances in Modern Oncology Research, 3(5), 213. https://doi.org/10.18282/amor.v3.i5.233

Li, L.-Y., Ma, R.-L., Du, L., & Wu, A.-S. (2017). Ozonated autohemotherapy modulates the serum levels of inflammatory cytokines in gouty Patients. Journal of Open Access Rheumatology: Research and Reviews.

Partridge, V., Sousares, M., Zhao, Z., & Du, L. (2017). Current understanding on the role of cell cycle regulators in neuroblastoma. Med One, 2, e170010. https://doi.org/10.20900/mo.20170010

Zhang, Y., Ma, X., Yu, X., Patolia, H., Zhao, Z., Du, L., & Pertsemilidis, A. (2017). ncRNA regulation of eribulin response in neuroblastoma. Cancer Research, 77(13 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/77/13_Supplement/3506

Yu, X., Ma, X., Zhang, Y., Zhao, Z., Du, L., & Pertsemilidis, A. (2017). Therapeutic potential of miR-195 in nonsmall cell lung cancer. Cancer Research, 77(13 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/77/13_Supplement/5444

Sousares, M., & Du, L. (2017). MicroRNA-506-3p as a Differentiation Agent for Neuroblastoma. FASEB Journal, 31(No.1 Suppl). Retrieved from www.fasebj.org/content/31/1_Supplement/757.18

Partridge, V., & Du, L. (2017). The Role of CDKN3 in Neuroblastoma Differentiation. FASEB Journal, 31(No.1  Suppl). Retrieved from http://www.fasebj.org/action/doSearch?AllField=The+Role+of+CDKN3+in+Neuroblastoma+Differentiation

Zhao, Z., Ma, X., Shelton, S. D., Sung, D. C., Li, M., Hernandez, D., … Du, L. (2016). A combined gene expression and functional study reveals the crosstalk between N-Myc and differentiation-inducing microRNAs in neuroblastoma cells. Oncotarget, 7(48), 79372–79387. https://doi.org/10.18632/oncotarget.12676

Yu, X., Zhao, Z., Ma, X., Du, L., & Pertsemilidis, A. (2016). miR-195 represses the tumorigenesis of non-small cell lung cancer and synergizes with microtubule targeting agents. Cancer Research, 76(14 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/76/14_Supplement/1063

Ma, X., Yu, X., Zhao, Z., Patolia, H., Du, L., & Pertsemilidis, A. (2016). Non-coding RNA regulation of eribulin response in neuroblastoma. Cancer Research, 76(14 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/76/14_Supplement/1940

Zhao, Z., Ma, X., Sung, D., Li, M., Kosti, A., Lin, G., … Du, L. (2015). microRNA-449a functions as a tumor suppressor in neuroblastoma through inducing cell differentiation and cell cycle arrest. RNA Biology, 12(5), 538–554.

Borkowski, R., Du, L., Zhao, Z., McMillan, E., Kosti, A., Yang, CR., … Pertsemlidis, A. (2015). Genetic Mutation of p53 and Suppression of the 3 miR-17-92 Cluster Are Synthetic Lethal in Non–Small Cell Lung Cancer due to Upregulation of Vitamin D Signaling. Cancer Research, 75(4), 666–675. https://doi.org/10.1158/0008-5472

Zhao, Z., Ma, X., Hsiao, TH., Lin, G., Kosti, A., Yu, X., … Du, L. (2014). A high-content morphological screen identifies novel microRNAs that regulate neuroblastoma cell differentiation. Oncotarget, 5(9), 2499–2512.

Liqin Du, Zhao, Z., Ma, X., Hsiao, TH., Chen, Y., Young, E., … Pertsemlidis, A. (2014). miR-93-directed down-regulation of DAB2 defines a novel oncogenic pathway in lung cancer. Oncogene, 33, 4307–4315.

Zhao, Z., Ma, X., Yu, X., Minna, J. D., Pertsemilidis, A., & Du, L. (2014). LMO1 is a novel oncogene in neuroendocrine lung cancer. Cancer Research, 74(19 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/74/19_Supplement/466

Yu, X., Zhao, Z., Ma, X., Du, L., & Pertsemilidis, A. (2014). A high-throughput screen identifies microRNAs regulating lung cancer cell survival and response to paclitaxel. Cancer Research, 74(19 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/74/19_Supplement/3545

Du, L., Borkowski, R., Zhao, Z., Yu, X., Ma, X., & Pertsemlidis, A. (2013). A high-throughput screen identifies miRNA inhibitors regulating lung cancer cell survival and response to paclitaxel. RNA Biology, 10(11), 1700–1713.

DeSevo, C., Du, L., Behrens, C., Wistuba, I., Minna, J. D., & Pertsemilidis, A. (2013). miR-10a regulates PI3K signaling and paclitaxel response in NSCLC. Cancer Research, 73(8 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/73/8_Supplement/3049

Du, L., Zhao, Z., Young, E., Ma, X., Wistuba, I., & Pertsemilidis, A. (2013). miR-93-directed down-regulation of Dab2 defines a novel oncogenic pathway in lung cancer. Cancer Research, 73(8 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/73/8_Supplement/3096

Du, L., Subauste, MC., DeSevo, C., Zhao, Z., Baker, M., Borkowski, R., … Pertsemlidis, A. (2012). miR-337-3p and its targets STAT3 and RAP1A modulate taxane sensitivity in non-small cell lung cancers. PLoS ONE, 7(6), e39167.

Du, L., & Pertsemlidis, A. (2012). microRNA regulation of cell viability and drug sensitivity in lung cancer. Exp Opin Biol Ther, 12(9), 1221–1239.

Du, L., DeSevo, C., Borkowski, R., Baker, M., Minna, J. D., & Pertsemilidis, A. (2012). microRNA regulation of cell viability and drug response in cancer. Cancer Research, 72(8 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/72/8_Supplement/140

DeSevo, C., Du, L., Behrens, C., Minna, J. D., & Pertsemilidis, A. (2012). miR-10a regulation of PIK3CA and response to taxol in non small cell lung cancer. Cancer Research, 72(2 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/72/2_Supplement/A2

Du, L., DeSevo, C., Borkoski, R., Baker, M., Minna, J. D., & Pertsemilidis, A. (2012). microRNA regulation of cell viability and drug sensitivity in lung cancer. Cancer Research, 72(2 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/72/2_Supplement/B7

Nikolic, D., Calderon, L., Du, L., & Post, SR. (2011). SR-A ligand and M-CSF dynamically regulate SR-A expression and function in primary macrophages via p38 MAPK activation. BMC Immunol, 12, 37–46.

Subauste, MC., Ventura-Holman, Du, L., Sansoma, OJ., & Maher, JF. (2011). Fem1b antigen in the stool of Apc (Min) mice as a biomarker of early Wnt signaling activation in intestinal neoplasia. Cancer Epidemiol, 35(1), 97–100.

Du, L., & Pertsemlidis, A. (2011). Cancer and neurodegenerative disorders: pathogenic convergence through microRNA regulation. J Mol Cell Biol, 3(3), 176–180.

Borkowski, R., Du, L., Minna, J. D., Gazdar, A. F., & Pertsemilidis, A. (2011). A miRNA inhibitor screen for synthetic lethal interactions in KRAS-driven NSCLC. Cancer Research, 71(8 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/71/8_Supplement/3958

Du, L., Subauste, M. C., Baker, M., DeSevo, C. F., & Pertsemilidis, A. (2011). miR-337-3p and its targets STAT3 and RAP1A modulate paclitaxel sensitivity in non-small cell lung cancers (NSCLCs). Cancer Research, 71(8 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/71/8_Supplement/4709

Du, L., Schageman, JJ., Irnov, Girard, L., Hammond, SM., Minna, JD., … Pertsemlidis, A. (2010). microRNA expression distinguishes SCLC from NSCLC lung tumor cells and suggests a possible pathological relationship between SCLCs and NSCLCs. J Exp Clin Cancer Res, 29, 75.

Subauste, MC., Sansom, OJ., Porecha, N., Raich, N., Du, L., & Maher, JF. (2010). Fem1b, a proapoptotic protein, mediates proteasome inhibitor-induced apoptosis of human colon cancer cells. Mol Carcinog, 49(2), 105–113.

Du, L., & Pertsemlidis, A. (2010). microRNAs and lung cancer: tumors and 22-mers. Cancer Metastasis Rev, 29(1), 109–122.

Subauste, MC., Ventura-Holman, T., Du, L., Subauste, JS., Chan, SL., Yu, VC., & Maher, JF. (2009). RACK1 downregulates levels of the pro-apoptotic protein Fem1b in apoptosis-resistant colon cancer cells. Cancer Biol Ther, 8(23), 2297–2305.

Gibbons, DL., Lin, W., Creighton, CJ., Rizvi, ZH., Gregory, PA., Goodall, GJ., … Kurie, JM. (2009). Contextual extracellular cues promote tumor cell EMT and metastasis by regulating miR-200 family expression. Genes Dev, 23(18), 2140–2151.

Du, L., Schageman, JJ., Subauste, MC., Saber, B., Hammond, SM., Prudkin, L., … Pertsemlidis, A. (2009). miR-93, miR-98 and miR-197 regulate expression of tumor suppressor gene. FUS1. Mol Cancer Res, 7(8), 1234–1243.

Du, L., Saber, B. C., Rachel, G., Gazdar, A. F., White, M., Minna, J. D., & Pertsemilidis, A. (2009). Abstract# 1381: miR-337 modulates sensitivity to paclitaxel in non_small cell lung cancer. Cancer Research, 69(9 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/69/9_Supplement/1381.short

Calderon, L. E., Du, L., Nikolic, D., & Post, S. R. (2008). Regulation of class a scavenger receptor expression by M-CSF: The” Ups” and” Downs” of SR-A. Arteriosclerosis, Thrombosis, and Vascular Biology, 28(6), E121.

Du, L., Greer, R., Schageman, J., Gazdar, A., White, M., Minna, J. D., & Pertsemilidis, A. (2008). microRNA regulation of chemoresistance in non-small cell lung cancer (NSCLC). Cancer Research, 68(9 Supplement). Retrieved from https://cancerres.aacrjournals.org/content/68/9_Supplement/5042.short

Post, S. R., Du, L., & Nikolic, D. (2005). M-csf Stimulates SR-A Expression in Macrophages via the Ptx-Sensitive Activation of P38 Kinase. Arteriosclerosis, Thrombosis, and Vascular Biology, 25(5), 114.

Du, L., & Post, S. (2004). Macrophage-colony stimulating factor differentially regulates low-density lipoprotein and transferrin receptor. J Lipid Res, 45(9), 1733–1740.

Du, L. (2004). Regulation of LDL receptor-mediated endocytosis by microphage-colony stimulating factor. Lexington, KY, United States. Retrieved from https://search.proquest.com/openview/10d54f8a418acc090fb047e8fb7fc8a8/1?pq-origsite=gscholar&cbl=18750&diss=y

Du, L., & Post, S. R. (2001). Microphage-colony stimulating factor differentially regulates transferrin and LDL receptor-mediated endocytosis. Circulation, 71(17), 233–233.